منابع مشابه
Capsaicin, Nociception and Pain.
Capsaicin, the pungent ingredient of the hot chili pepper, is known to act on the transient receptor potential cation channel vanilloid subfamily member 1 (TRPV1). TRPV1 is involved in somatic and visceral peripheral inflammation, in the modulation of nociceptive inputs to spinal cord and brain stem centers, as well as the integration of diverse painful stimuli. In this review, we first describ...
متن کاملLacking the Capsaicin Receptor Impaired Nociception and Pain Sensation in Mice
www.sciencemag.org (this information is current as of January 3, 2007 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/288/5464/306 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/288/5464/306#otherarticles , ...
متن کاملCapsaicin and pain mechanisms.
Capsaicin, the active ingredient in hot chilli peppers, has selective actions on unmyelinated C-fibres and thinly myelinated A primary sensory neurones [37, 100] (Table 1). Most capsaicin-sensitive fibres are polymodal nociceptors which respond to a range of sensory stimuli including noxious pressure, heat and chemical irritants [51, 100], and are the most abundant class of nociceptive fibre. N...
متن کاملNociception and Pain in Animals
Recent evidence has shown that fi sh display aversive behavioral and physiological reactions and a suspension of normal behavior in response to noxious stimuli that cause pain in other animals and humans. In addition to these behavioral responses, scientists have identifi ed a peripheral nociceptive system and recorded specifi c changes in the brain activity of fi sh during noxious stimulation....
متن کاملProstanoids in nociception and pain.
Prostaglandins are lipid mediators produced by cyclooxygenases from arachidonic acid, which serve pivotal functions in inflammation and pain. Inhibition of their production is the major analgesic mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs)-but also the source of most of their unwanted effects. While the development of selective inhibitors of inducible cyclooxygenase (C...
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ژورنال
عنوان ژورنال: Molecules
سال: 2016
ISSN: 1420-3049
DOI: 10.3390/molecules21060797